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Propargyl Chloride 624-65-7

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MOQ : 50 Kilograms

Propargyl Chloride 624-65-7 Specification

EINECS No
210-848-4

Usage
For synthesis of pharmaceuticals, agrochemicals, and specialty chemicals

CAS No
1896-62-4

Melting Point
-78 C

Density
1.046 Gram per cubic centimeter(g/cm3)

Properties
Highly reactive, lachrymatory, colorless to light yellow liquid

Application
Used as an alkylating agent, intermediate in pharmaceuticals, organic synthesis

HS Code
29109090

Shape
Liquid form

Purity
>98%

Storage
Store in cool, dry, well-ventilated area in tightly closed container

Solubility
Insoluble in water, soluble in most organic solvents

Product Type
Organic Intermediate

Molecular Weight
74.51 g/mol

Molecular Formula
C3H3Cl

Physical Form
Liquid

Structural Formula
ClCH2CCH

Shelf Life
12 months from date of manufacturing

Ingredients
Propargyl Chloride (3-Chloro-1-propyne)

Smell
Pungent, irritating odor

Appearance
Clear pale yellow to colorless liquid

Poisonous
YES

Refractive Rate
1.4240 - 1.4280

Grade
Technical, Laboratory

Boiling Point
80-81 C

Transport Information
Transport according to regulations for hazardous chemicals

Autoignition Temperature
Not established

Handling Precautions
Handle with suitable protective equipment; avoid inhalation and skin contact

UN Number
2398

Hazard Class
6.1 (Toxic substances)

Packing Group
II

Vapor Pressure
53 mm Hg at 20C

Stability
Stable under recommended storage conditions

Flash Point
16 C (Closed cup)

Propargyl Chloride 624-65-7 Trade Information

Minimum Order Quantity
50 Kilograms

Supply Ability
500000 Kilograms Per Year

Delivery Time
30 Days

Main Export Market(s)
Australia, North America, Eastern Europe, Middle East, South America, Asia, Western Europe, Central America, Africa

About Propargyl Chloride 624-65-7

Propargyl Chloride

CAS No.: 624657
Molecular formula: CHCl
Water-solubility: Little soluble in water
Assay: 99
Appearance: Colorless and transparent liquid

Application: As a propargyl precursor, it is used many kinds of synthesis and pharmaceutical and electroplating chemical intermediates. In addition, it is a good corrosion inhibitor and anti-rust. And could be weed killer.

Key Features and Chemical Properties

Propargyl Chloride is valued for its high reactivity and purity, making it a preferred intermediate in laboratories and industrial synthesis. It appears as a clear, pale yellow liquid, emitting a strong, irritating odor typical of lachrymatory agents. With a melting point of -78C and a boiling point near 81C, it is stable under recommended storage. Although insoluble in water, it dissolves readily in most organic solvents, providing versatility across applications.

Safe Storage and Handling

Due to its toxic and highly reactive nature, Propargyl Chloride should always be handled with appropriate protective equipment. Store it in tightly sealed containers in a cool, dry, and well-ventilated space, away from ignition sources. Any transport must comply with hazardous chemical regulations, as reflected by its Hazard Class (6.1) and Packing Group II status. Strict adherence to safety precautions helps ensure both product integrity and personnel safety.

Applications and Industrial Use

Propargyl Chloride serves as an essential building block in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its alkylating properties facilitate a variety of chemical transformations, making it useful in both research and commercial manufacturing settings. As a technical and laboratory-grade product, its high purity and reactivity are significant benefits for chemists and process engineers seeking reliable performance in organic synthesis.

FAQ's of Propargyl Chloride 624-65-7:

Q: How should Propargyl Chloride be safely handled and stored?

A: Propargyl Chloride must be handled with suitable protective equipment, such as chemical-resistant gloves, goggles, and lab coats. Always avoid inhalation of vapors and skin contact. For storage, keep the chemical in a tightly sealed container in a cool, dry, and well-ventilated area, away from sources of heat or ignition. Adhere to all safety data sheet and local regulatory guidelines.

Q: What are common applications of Propargyl Chloride?

A: This compound is widely used as an alkylating agent and intermediate in the synthesis of pharmaceuticals, agrochemicals, and specialty chemicals. Its high reactivity also allows for its use in various organic synthesis processes in both laboratory and industrial settings.

Q: When is Propargyl Chloride typically utilized during chemical synthesis?

A: Propargyl Chloride is generally introduced as a key intermediate when a reactive alkylating agent is required for introducing propargyl groups into target molecules. Its involvement often occurs at strategic stages to build complex structures in drug and agrochemical development.

Q: Where can Propargyl Chloride be sourced and who supplies it?

A: Supplied and distributed by manufacturers, exporters, and traders, primarily in China, Propargyl Chloride is available in technical and laboratory grades for both domestic and international markets. Buyers should ensure suppliers meet regulatory and purity standards.

Q: What is the process for transporting Propargyl Chloride?

A: Transport of Propargyl Chloride must follow regulations for hazardous chemicals (UN Number 2398, Hazard Class 6.1, Packing Group II). Containers should be properly labeled and secure to prevent leaks, and all legal documentation must accompany shipments.

Q: Why is Propargyl Chloride considered beneficial in organic synthesis?

A: Owing to its high reactivity and ability to introduce versatile alkyne functionalities, Propargyl Chloride enables the construction of complex chemical architectures, which is invaluable in pharmaceutical and specialty chemical manufacturing.

Q: What precautions should be observed due to the hazardous properties of Propargyl Chloride?

A: Because it is toxic, lachrymatory, and flammable (flash point 16C), it is important to handle it only in well-ventilated areas with full protective gear. Avoid all direct contact, and have appropriate spill control and emergency procedures in place during handling and use.

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